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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RFC1
All Species:
9.09
Human Site:
S1090
Identified Species:
18.18
UniProt:
P35251
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35251
NP_002904.3
1148
128255
S1090
S
R
H
S
T
S
P
S
L
D
S
E
Y
N
E
Chimpanzee
Pan troglodytes
XP_001140765
1148
128250
S1090
S
R
H
S
T
S
P
S
L
D
S
E
Y
N
E
Rhesus Macaque
Macaca mulatta
XP_001091287
1148
128475
S1090
S
R
H
S
T
S
P
S
L
D
S
E
Y
N
E
Dog
Lupus familis
XP_536259
1145
128125
A1087
P
R
H
S
T
G
P
A
L
D
S
E
Y
N
E
Cat
Felis silvestris
Mouse
Mus musculus
P35601
1131
125967
A1074
S
R
L
S
T
G
P
A
L
D
S
E
Y
S
E
Rat
Rattus norvegicus
NP_445999
1131
125770
A1072
S
R
P
S
I
G
P
A
L
D
S
E
Y
N
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512744
1233
136122
G1170
S
K
R
G
A
G
L
G
L
G
P
A
L
E
G
Chicken
Gallus gallus
NP_001006456
1147
128454
M1085
S
R
R
Q
S
G
S
M
G
T
S
E
L
N
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P35600
986
108596
E929
Y
L
D
E
G
P
G
E
E
D
G
A
G
G
H
Honey Bee
Apis mellifera
XP_397246
911
103001
E854
N
V
Q
E
E
G
L
E
E
E
E
E
E
V
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797949
906
99249
M849
A
G
V
E
D
G
L
M
K
V
E
G
E
E
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38630
861
94885
F804
T
S
T
S
T
P
D
F
E
D
V
V
D
A
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.3
89.3
N.A.
82.4
81.3
N.A.
67.4
68.9
N.A.
N.A.
N.A.
39.9
36.2
N.A.
38
Protein Similarity:
100
99.6
98.5
93.7
N.A.
89.5
88.5
N.A.
77.2
79.6
N.A.
N.A.
N.A.
55.9
53.6
N.A.
52.2
P-Site Identity:
100
100
100
80
N.A.
73.3
73.3
N.A.
13.3
40
N.A.
N.A.
N.A.
6.6
6.6
N.A.
0
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
80
N.A.
20
46.6
N.A.
N.A.
N.A.
6.6
26.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
9
0
0
25
0
0
0
17
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
9
0
9
0
0
67
0
0
9
0
25
% D
% Glu:
0
0
0
25
9
0
0
17
25
9
17
67
17
17
59
% E
% Phe:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
9
0
9
9
59
9
9
9
9
9
9
9
9
9
% G
% His:
0
0
34
0
0
0
0
0
0
0
0
0
0
0
9
% H
% Ile:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
9
0
0
0
0
0
0
9
0
0
0
0
0
0
% K
% Leu:
0
9
9
0
0
0
25
0
59
0
0
0
17
0
0
% L
% Met:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
0
0
0
0
0
0
0
0
0
50
0
% N
% Pro:
9
0
9
0
0
17
50
0
0
0
9
0
0
0
0
% P
% Gln:
0
0
9
9
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
59
17
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
59
9
0
59
9
25
9
25
0
0
59
0
0
9
0
% S
% Thr:
9
0
9
0
50
0
0
0
0
9
0
0
0
0
0
% T
% Val:
0
9
9
0
0
0
0
0
0
9
9
9
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
0
0
0
0
50
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _